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Najstarsza forma domów sa jaskinie (paleolit), szalasy, ziemianki (mezolit). Zupa domy uprzedni jednoizbowe (neolit), w epoce brazu natomiast zelaza wystepuja w tym momencie trzyizbowe (Biskupin). Wznoszono je sposród galezi oblepianych glina, drewna tudziez kamienia. W okresie starozytnym w Egipcie, Mezopotamii budowano domy z cegiel recznie lepionych z gliny zas suszonych na sloncu. Wczesniejszy to budynki wieloizbowe, raz za razem z dziedzincem wewnetrznym, w owym czasie pojawily sie tez budynki pietrowe. W Europie, wyksztalcil sie budynek wolnostojacy grecki natomiast budynek wolnostojacy rzymski. Wraz sposród upadkiem cesarstwa rzymskiego nastapilo zalamanie rozwoju budownictwa. Tradycje domu rzymskiego kontynuowala architektura islamu.
W Europie chrzescijanskiej, w okresie wczesnego sredniowiecza funkcje domów pelnily warowne zamki a drewniane chaty budowane na terenie grodów natomiast podgrodzi czy tez w charakterze rozproszone (wies), na terenach chronionych w sposób prosty – np. w lesie. W miastach w wieku XIII a XIV budynek wolnostojacy to glównie budowla o drewnianej konstrukcji szkieletowej, które zaczeto zmieniac budynkami o scianach murowanych (budynki w konstrukcji "muru pruskiego" wznoszono coraz na poczatku XX w.). W okresie gotyku w budownictwie miejskim zaczeto podnosic przewaznie dwu-, trzypietrowe kamienice szczytowe. Parter asygnowany byl na kurs rzemieslnicze natomiast sklepiki, pietro sluzylo jak akt mieszkalna, tudziez na poddaszu wczesniejszy magazyny. Poczawszy od momentu renesansu, miejskie kamienice zyskuja szersze, bogato zdobione fasady sposród wiekszymi oknami, wzrasta wolumen pomieszczen, wewnatrz budowane sa arkadowe dziedzince. Wystepuja oraz kamienice sposród podcieniami zas dachy sposród attykami. ów odmiana budownictwa w okresie baroku zaczal wypelniac dodatkowo funkcje miejskich rezydencji przedstawicieli najwyzszych warstw spolecznych. Kamienice upodobnily sie az do miejskich palaców.
Na terenach wiejskich zabudowa warowna przeobrazila sie w palace zas dworki szlacheckie.
Budownictwo jednorodzinne wyksztalcilo sie w Anglii w XVII w. Kamienice czynszowe pojawily sie na poczatku XVIII w. w miastach Anglii a Francji (pierwsze domy czynszowe znano w tym momencie w czasach starozytnych w Grecji oraz w Rzymie – insula). W czasach dzisiejszych funkcje domów pelnia budynki wielorodzinne (bloki mieszkalne, kamienice) tudziez jednorodzinne.
Domy wspólczesne

Budynki wielorodzinne: Le Corbusier propagowal idee masowego budownictwa mieszkalnego. Jego projekty zabudowy w zamian opieraly sie na wyodrebnieniu funkcji mieszkalnej, wypoczynkowej a sfer pracy (biura, zaklady przemyslowe). Domy – jednakowe wiezowce, pozbawione ozdób, o geometrycznych ksztaltach, sytuowane w poblizu parków, przeznaczone uprzedni dla setek i tysiecy osób. Z tych zalozen wywodza sie dzisiejsze osiedla realizowane w Polsce odkad lat szescdziesiatych XX w. Odkad poczatku lat 90. XX wieku, po zmianie systemu gospodarczego, raz za razem popularniejsze sa domy jednorodzinne. W XXI wieku raz za razem popularniejsze sa scisle mówiac zwane domy kanadyjskie.
Budynki jednorodzinne budowane sa na terenach wiejskich a miejskich w charakterze mozna stojace natomiast w zabudowie blizniaczej (dwa domy posiadajace jedna sciane wspólna), szeregowej (szereg budynków o wspólnych scianach bocznych), czasem atrialnej (okreslenie pochodzi od atrium) – sa to budynki jednorodzinne, np. o rzucie w ksztalcie litery "L" lub "C" z wewnetrznymi miniogródkami. Na obszarach w zastepstwie oraz osiedli podmiejskich tworza czasem samodzielne zespoly urbanistyczne z wlasnymi sklepami, szkolami, osrodkami zdrowia itp.
Funkcje mieszkalne zaspokajaja oraz budynki takie gdy hotele, internaty, koszary.
Poza Europa wyksztalcily sie oraz inne formy budynków mieszkalnych. Spowodowane to bylo innymi warunkami klimatycznymi tudziez zróznicowana dostepnoscia materialów az do wznoszenia domów.
Ze wzgledu na straty ciepla w tej chwili budowane domy wolno podzielic na:
domy konwencjonalne,
domy energooszczedne,
domy pasywne.
Ze wzgledu na werbunek energii tudziez wody domy mozemy podzielic na:
domy konwencjonalne,
domy autonomiczne, tzn. takie które z racji instalacji do zbierania wody deszczowej, ogrzewaniu slonecznemu, wlasnym wytwornicom pradu, toaletom kompostujacym a uzyciu tzw. szarej wody nie wymagaja przylaczenia do jakichkolwiek mediów.

ieszkanie – zgodnie sposród normatywna definicja zamieszczona w rozporzadzeniu Ministra Infrastruktury z dnia 12 kwietnia 2002 r. w sprawie warunków technicznych, jakim powinny konweniowac budynki i ich sytuacja (Dz. Obok. Nr 75 poz. 690 z pózn. zm.) – obowiazujacym od czasu dnia 16 grudnia 2002 – mieszkaniem jest calosc pomieszczen mieszkalnych tudziez pomocniczych, majacy odrebne dojscie, wydzielony stalymi przegrodami budowlanymi, umozliwiajacy sztywny przebywanie ludzi i prowadzenie samodzielnego gospodarstwa domowego.
Wsród form budownictwa mieszkaniowego wyróznia sie mieszkania:
spóldzielcze (oddane do uzytku przez spóldzielnie mieszkaniowa w celu czlonków tej spóldzielni),
komunalne (budowane w srodku finanse z budzetu gminy, sa owo mieszkania socjalne tudziez interwencyjne),
przeznaczone na sprzedaz a wynajem,
spoleczno-czynszowe (realizowane za posrednictwem Asysta Budownictwa Spolecznego w ciagu finanse Krajowego Funduszu Mieszkaniowego)
indywidualne,
zakladowe.
W Polsce gielda najmu mieszkan powinno sie do z najslabiej rozwinietych w Europie]. Przystepnosc nowego mieszkania jak wlosc w relacji az do przecietnego wynagrodzenia w poszczególnych miastach w Polsce jest zróznicowana w zaleznosci odkad regionu].
Zobacz tez

Inwentaryzacja - caloksztalt czynnosci rachunkowych zmierzajacych az do sporzadzenia szczególowego spisu z natury skladników majatkowych a zródel ich pochodzenia na zdefiniowany dwadziescia cztery godziny. Remanent polega na ustaleniu za pomoca spisu faktycznego stanu wszystkich rzeczowych natomiast pienieznych skladników majatkowych, kiedy podobnie interpretacja róznic miedzy stanem stwierdzonym w trakcie inwentaryzacji (rzeczywistym), a stanem wynikajacym z ewidencji ksiegowej.
Róznice te wynikaja po najwiekszej czesci sposród dwóch nastepujacych powodów:
zmiany naturalnych cech przedmiotów, których nie mozna wynegocjowac na podstawie dowodów (ulatnianie sie, wysychanie, niedokladny eksperyment przyjecia oraz wydania materialów masowych, przeterminowanie zapasów, zmiany mody itp.);
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Zgodnie z obowiazujacymi przepisami, inwentaryzacja dotyczy nastepujacych czynnosci:
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wskazania sposobów usuniecia nieprawidlowosci w gospodarce majatkiem jednostki.
Rozróznia sie nastepujace rodzaje inwentaryzacji:
spis z natury - dokonywany za pomoca czlonków komisji inwentaryzacyjnej, na podstawie bezposrednich obserwacji i pomiarów srodków majatkowych w jednostce gospodarczej. Obejmuje mozliwe do obejrzenia srodki trwale, rzeczowe zawartosc majatku obrotowego, srodki pieniezne w kasie, papiery wartosciowe. Zgodnie z art. 26 ustawy o rachunkowosci inwentaryzacja droga spisu z natury obejmuje sie równiez znajdujace sie w jednostce sklad aktywów, bedace wlasnoscia innych jednostek, powierzone jej do sprzedazy, przechowania, przetwarzania badz uzywania, powiadamiajac te jednostki o wynikach spisu. Obowiazek ten nie dotyczy jednostek swiadczacych uslugi pocztowe, transportowe, spedycyjne i skladowania.
uzgadnianie sald sposród kontrahentami - obejmuje postac srodków pienieznych na rachunkach bankowych, pozyczki oraz kredyty, naleznosci, zobowiazania.
weryfikacja stanu ewidencyjnego - dotyczy aktywów oraz pasywów, których stanu nie mozna porozumiec sie dzieki spis inwentaryzacyjny wzglednie skoordynowanie sald z kontrahentami. Dotyczy to w szczególnosci gruntów rolnych, naleznosci tudziez zobowiazan publicznoprawnych natomiast innych skladników niemozliwych az do obejrzenia.
Inwentaryzacje srodków majatkowych oraz zródel ich pochodzenia w jednostce gospodarczej przeprowadza sie co w zadnym razie uderzenie w kazdym roku obrotowym, zazwyczaj na zeszly doba roku obrotowego.
Za poprawne zas terminowe egzekucja inwentaryzacji zadluzenia ponosi kierownik jednostki.
Inwentaryzacja powinna znajdowac sie istotnie zorganizowana, tak aby normalna aktywnosc jednostki gospodarczej nie zostala przerwana.
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Apteka – zespól, zajmujaca sie po najwiekszej czesci sprzedaza leków a innych produktów medycznych (np. opatrunków, srodków higienicznych). Apteki recepturowe zajmuja sie dodatkowo przygotowywaniem leków recepturowych zgodnie sposród przepisana przy uzyciu lekarza recepta. W praktyce pacjenci korzystaja w aptekach plus z konsultacji medycznych w sprawie stosowania poszczególnych leków w przypadku konkretnych dolegliwosci, i nawet, w naglych przypadkach, sposród najbardziej podstawowej pomocy medycznej, polegajacej na udzieleniu pierwszej pomocy oraz wezwaniu innego wykwalifikowanego personelu (lekarza, felczera, zespolu pogotowia ratunkowego itp.).
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Apteka kieruje aptekarz po studiach farmaceutycznych, spelniajacy plus klauzula piecioletniego stazu pracy w aptece; wyjawszy poprzednio ustawa wydawania leków (pracy pod reka pierwszym stole, gdy owo okreslaja sami farmaceuci) maja wprost przeciwnie inni farmaceuci (magistrzy, jak sie przyjelo ujmowac wszystkich farmaceutów) i technicy farmaceutyczni. Robota tego personelu po czesci wierzch sie sposród praca magistrów farmacji natomiast obejmuje przede wszystkim sporzadzanie, wytwarzanie i wydawanie produktów leczniczych i wyrobów medycznych.
W Polsce dzieki praktycznie cale powojenne pólwiecze (nie liczac kilku lat po 1945 roku) apteki mogly znajdowac sie zaledwie wlasnoscia panstwowa a podlegaly Centralnemu Zarzadowi Aptek. Po roku 1989 kodeks prawa zmienily sie w ów tryb, ze wlascicielami aptek moga znajdowac sie takze osoby prywatne; istnial wzorzec, aby sprowadzic norma prawna posiadania apteki nic bardziej blednego wykwalifikowanym farmaceutom, niemniej jednak intencja to nie powiodlo sie, totez nie wszyscy wlasciciele aptek uznaja potrzebe respektowania zasad etyki zawodowej. Fakt ten, tudziez plus niespójna tudziez niekonsekwentna dzialalnosc polityczna panstwa pod systemu opieki zdrowotnej w ogólnosci, w tym zasad refundacji kosztów leków, sa przyczyna obserwowanej w wielu miejscach sytuacji, ze niektóre apteki – pragnac umozliwic sobie jak najwieksza sprzedaz – w zastepstwie napelniac swoje glówne zadania w lancuchu placówek medycznych raz za razem w wyzszym stopniu poszerzaja spektrum sprzedazy specyfików paramedycznych oraz kosmetycznych. Wybór taki prawidlowo móglby znajdowac sie sprzedawany w kazdym sklepie wzglednie kiosku, nie wymaga jako ze od czasu osób przedtem handlujacych zadnych specjalnych kwalifikacji; sprzedawany natomiast w aptece wydaje sie potencjalnym nabywcom z wiekszym natezeniem wiarygodny tudziez skuteczniejszy, anizeli gdyby pochodzil sposród kiosku na rogu ulicy, stad producenci takich srodków zachecaja wlascicieli aptek az do podjecia sie ich dystrybucji. Odkad 2012 roku w polskich aptekach nie wolno oglaszac sprzedawanych produktów].
Specyficzna odmiana aptek sa zamkniete placówki wewnatrzszpitalne, pracujace wylacznie na potrzeby szpitala, nie obslugujace wrecz pacjentów. Wymagania stawiane personelowi takich aptek praktycznie nie róznia sie od chwili wymagan stawianych osobom, pracujacym w aptekach otwartych. Tymczasem mianem "apteki leków gotowych" nazywa sie - w odróznieniu odkad "aptek recepturowych" – takie, w których nie przygotowuje sie leków wg receptury, oraz tylko sprzedaje sie gotowe specyfiki, w pierwszej chwili opakowane za posrednictwem producentów, wzglednie przepakowywane sposród wiekszych opakowan az do mniejszych ("fasowane"), zgodnie z zapotrzebowaniem pacjenta a przepisana z wykorzystaniem lekarza recepta.
Istnieja równiez apteki internetowe dzialajace na zasadach podobnych do sklepów internetowych.
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GREEN BAY, Wis. — Aaron Rodgers and the Green Bay Packers showed how dangerous they can be when they're at full strength Saturday night, overwhelming the Minnesota Vikings 24-10 in an NFC wild-card game that was never really close.
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Foster is a tremendous back, running behind a superb offensive line. Opening the playoffs with a 19-13 victory over the Cincinnati Bengals, Foster rushed for 140 yards and a touchdown on 32 carries. It was an impressive performance. The Bengals (10-7) are no cream puffs on defense, and defensive tackle Geno Atkins is one of the best in the business. But the Texans’ offensive line still opened holes for Foster, and he ran with power and passion.
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Fans of the Baltimore Ravens bid farewell to pe ( sjshseladw @ 2013-01-08 09:28:55 )
Reed, 34, has considered retirement after each of the last couple of seasons, and with his contract due to expire at season's end, it may be a natural stopping point for the ball-hawking safety.

But after Sunday's win over the Indianapolis Colts, Reed insisted that his sole focus was on next week's game at Denver, not his future.
Wild Card Weekend: Wilson sparks Seattle ( sjduweladw @ 2013-01-08 10:04:34 )
You have to wonder how this game would have turned out if Robert Griffin III hadn't tweaked his knee in the first quarter and erased any chance he had of being effective under center.

Or if Redskins coach Mike Shanahan had turned the offense over to Kirk Cousins, who has shown in the past that he can win games (as a backup and as a starter). Instead, Griffin might have hurt himself even worse in the fourth quarter on a botched snap, and Cousins had little chance to overcome a 10-point deficit.
Fans of the Baltimore Ravens bid farewell to pe ( sjshseladw @ 2013-01-08 12:47:59 )
Reed, 34, has considered retirement after each of the last couple of seasons, and with his contract due to expire at season's end, it may be a natural stopping point for the ball-hawking safety.

But after Sunday's win over the Indianapolis Colts, Reed insisted that his sole focus was on next week's game at Denver, not his future.
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Bruce Arians released from hospital, resting at home ( swwwduwels @ 2013-01-10 07:03:24 )
Colts offensive coordinator Bruce Arians has been released from an Indianapolis hospital, and he plans to rest for a few days before starting interviews for open head-coaching positions with NFL teams, NFL.com's Ian Rapoport reported Wednesday.

No interviews have been scheduled, but NFL teams reportedly interested in meeting with Arians include the Philadelphia Eagles, Cleveland Browns, Chicago Bears and San Diego Chargers. On Wednesday, the Chargers hired Tom Telesco, the Colts' former vice president of football operations, as their new general manager
Cowboys' Rob Ryan out ( mmmhseladw @ 2013-01-10 09:15:46 )
The Dallas Cowboys fired defensive coordinator Rob Ryan on Tuesday, according to multiple reports.

Ryan was let go after the Cowboys missed the postseason for a third consecutive year. His firing ends a two-year tenure with the team.
Under Ryan's tutelage, the Cowboys ranked among the league's top 20 total defenses, placing 14th in 2011 but slipping to 19th in 2012, perhaps in large part as a result of injuries to many of Dallas' key defensive players.
Ryan becomes the second casualty of the Cowboys' coaching staff. Running backs coach Skip Peete was fired on Monday.
Cowboys' Rob Ryan out ( mmmhseladw @ 2013-01-10 12:29:53 )
The Dallas Cowboys fired defensive coordinator Rob Ryan on Tuesday, according to multiple reports.

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Under Ryan's tutelage, the Cowboys ranked among the league's top 20 total defenses, placing 14th in 2011 but slipping to 19th in 2012, perhaps in large part as a result of injuries to many of Dallas' key defensive players.
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Where in the world is Todd Haley? ( suewhwgsxx @ 2013-01-12 14:02:51 )
Where in the world is Todd Haley? With the Arizona Cardinals looking for their next head coach, we have conflicting reports on the Pittsburgh Steelers offensive coordinator's whereabouts.

A source close to Haley first told NFL.com's Ian Rapoport the coach won't meet with the Cardinals after the team requested permission for an interview.
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Division of labor – TimeSvr says they have a trained group of English speaking aides that are assigned to be especially good at specific tasks.
Scales very well – Unlimited tasks for $59 a month.  They have other plans for businesses and groups who need dedicated, 6 day a week aides that I did not try out – but it’s available as an option.  For businesses and groups (or I guess an individual, if you really need this much help), a dedicated aide available 9 hours a day, 6 days a week, costs $950 per month – very cheap, about $4 an hour.
Progress for multiple tasks can be tracked via their dashboard.
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DOT Assistant LLC assistant is Always available. Whether via email, their dashboard interface, skype or over the phone, I never had an issue getting my tasks completed.  I tried to assign tasks at as odd hours as I could – they always completed the relatively easy ones (5-15 minutes of work) within ~45 minutes, often much sooner. Clearly, they are serious about providing round the clock service.
DOT Assistant LLC assistant Consistent quality – again, provided the tasks are well defined
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精准医疗又叫个性化医疗,是指以个人基因组信息为基础,结合蛋白质组,代谢组等相关内环境信息,为病人量身设计出最佳治疗方案,以期达到治疗效果最大化和副作用最小化的一门定制医疗模式。因此相较传统医疗,精准医疗具有针对性、高效性及预防性等特征。

美国医学界在2011年首次提出了“精准医学”的概念,今年1月20日,奥巴马又在美国国情咨文中提出“精准医学计划”,希望精准医学可以引领一个医学新时代。10月8日,2015全球创新论坛纽约峰会在纽约穆迪总部大楼举办。乐土投资集团CEO刘如银在峰会上介绍了他的精准医疗生态圈的想法。

刘如银介绍了乐土投资在美国的国际化实践,包括在美国的地产投资拓展,以及最新投资的医疗健康项目。乐土投资集团(CLIG)定位以硅谷的高科技投资为引擎,以科技医疗和互联网金融为两翼,链接最具价值的深科技健康项目,服务国际大健康和科技发展。

美国财政预算计划在2016年拨付给美国国立卫生研究院(NIH)、美国食品药品监督管理局(FDA)、美国国家医疗信息技术协调办公室(ONC)等机构共2.15亿美元用于资助这方面的科学研究与创新发展。

刘如银说:美国的精准医疗主要是围绕着基因组、蛋白组等方面的检测,也就是围绕分子生物学的特性,针对个体化的病理特征进行治疗。而我们所关注的不仅如此,更是系统化的,全过程、全要素、全局性的对医疗过程和临床实践进行优化。我们所指的精准医疗也是针对每一个病人的具体病情,正确选择并精确的应用适当的治疗方法。刘如银认为:精准医疗的最终目标是以最小化的医源性损害、最低化的医疗资源耗费去获得最大化的病患的效益,其前景不可限量。

精准医疗要做到个性、高效及预防的关键在于筛查和诊断,因此基因测序等检测诊断技术的发展是关键。成本的下降让基因测序商业化市场的打开成为可能,基因测序技术的成熟和商用经过了多年的发展,1980 年自动测序仪出现,2001 年完成了人类基因组框架图标志着这一技术的成熟,2007 年二代基因测序技术大幅降低测序成本,使得这一技术应用出现可能,以走在前列的Illumina 公司为例,该公司自2007 年起把当时每个基因组的测序成本费用从1000万美元降到了当下的1000 美元, 根据Illumina 公司数据,全球NGS(二代基因测序)的应用市场规模预计为200 亿美元,药品研发和临床应用是增速最快的领域,增速超过15%,肿瘤诊断和个性化用药是最有应用前景的领域,市场规模120亿美元。乐土投资与Illumina以及新一代的基因检测公司Genalyte, Centrillion都有着合作关系。

刘如银说:精准医疗作为医疗模式的革新对提高我国国民健康水平有重要意义,将在基因测序技术发展和国家政策的推动下迎来黄金发展期。精准治疗是下一个新兴朝阳行业,我们关注基因测序、肿瘤诊断及个性化用药等相关投资机会。

全球创新论坛纽约峰会由全美华人金融协会(The Chinese Finance Association, TCFA) 主办。全美华人金融协会于一九九四年在美国成立。分布在世界各地的会员来自华尔街投行、基金、监管部门、和学术界,已成为联系中美金融界最重要的桥梁之一。协会定期举行学术年会。协会本部设在纽约,并在波士顿,华盛顿,旧金山,伦敦,香港,北京和上海等金融中心设有分会。

原招商银行行长马蔚华,中信银行美国分行行长文兵,汉世纪投资管理有限公司合伙人吴皓,联合国南南合作办首席经济与投资专家杨庆宏等参加了本年度会议并发表了讲话。
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